Synthetic Route of 130-03-0, Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes.
The reaction of alkyl 4-(2-acetylhydrazino)-2-methyl-3- thiophenecarboxylates with 3-methylbutan-2-one was carried out under the Fischer reaction conditions. The influence of Lewis acids and solvents on the process was studied. A convenient method for the synthesis of thieno [3.2-b]pyrrolenine derivatives was proposed.
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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem