In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or syste. Electric Literature of 4923-87-9
Catalytic enantioselective conjunctive cross-coupling has been developed to construct tertiary alkylboronic esters. These reactions occur with good yield and enantioselectivity for a range of substrates. Mechanistic experiments reveal aspects of the catalytic cycle that allow hindered substrates to react without significant complicating side reactions.
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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem