Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. Recommanded Product: 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene, C15H10BrFS. A document type is Patent, introducing its new discovery., Recommanded Product: 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene
The invention discloses the Iraqi gliclazide net intermediate preparation method, including 2 – (3 – benzo [B] thiophene – 2 – yl methyl – 4 – fluoro – phenyl) – 3, 4, 5 – c – trimethyl siloxy – 6 – trimethyl siloxy methyl – tetrahydro – pyran – 2 – ol (compound 3) and (1 S) – 2, 3, 4, 6 – four-acetoxy – 1, 5 – dehydration – 1 – [3 – (1 – benzothiophene – 2 – yl methyl) – 4 – fluorophenyl] – D – sorbitol (compound 6) specific preparation method; wherein the control of the reaction temperature not higher than – 60 C under the premise, as soon as possible should be adds by drops positively BuLi, n-butyl and the faster the dropping speed, compound 3 of ortho-substituted F of less by-products, to ensure that the resulting compound 3 of purity, and had a direct impact on the resulting compound 6 yield, the present invention is amplified without amplifying effect, it is suitable for industrial production. (by machine translation)
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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem