Synthetic Route of 4923-87-9, New research progress on 4923-87-9 in 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. In a article, 4923-87-9, molcular formula is C8H5BrS, introducing its new discovery.
The first example of near-room-temperature alpha-arylation of benzo[b]thiophenes is reported. The discovery rests on the observation of a switch in alpha-/beta-regioselectivity at different loadings of Pd2(dba)3·CHCl3 in the coupling between benzo[b]thiophene and 4-iodotoluene. We show that this unprecedented regioselectivity switch is driven by a Ag(I)-mediated C-H activation at the alpha-C-H position, which becomes the dominant mode of reactivity at low concentrations of Pd. Competition experiments, kinetic studies, KIE, and D/H scrambling experiments have been carried out supporting this mechanism.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4923-87-9 is helpful to your research. Synthetic Route of 4923-87-9
Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem