With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5381-20-4,Thianaphthene-3-carboxaldehyde,as a common compound, the synthetic route is as follows.,5381-20-4
General procedure: To a round-bottom flask equipped with a magnetic stirring bar were added 3-diazoindolin-2-imines 1 (0.1mmol), aryl aldehydes (2) (0.15mmol), BF3·OEt2 (0.1mmol), and ethyl acetate (1mL) under air atmosphere. The mixture was stirred at room temperature for 2h. The resulted mixture was evaporated under reduced pressure and the residue was purified by flash column chromatography on a silica gel with petroleum ether/ethyl acetate (6:1, v/v) to give pure products 3.
As the paragraph descriping shows that 5381-20-4 is playing an increasingly important role.
Reference：
Article; Huang, Kai; Lu, Ping; Wang, Yanguang; Tetrahedron; vol. 75; 27; (2019); p. 3779 – 3787;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem