Electric Literature of 1034305-17-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 1034305-17-3, 2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene, introducing its new discovery.
Ni-Catalyzed Suzuki-Miyaura Cross-Coupling of alpha-Oxo-vinylsulfones to Prepare C-Aryl Glycals and Acyclic Vinyl Ethers
We demonstrate that readily available and bench-stable alpha-oxo-vinylsulfones are competent electrophiles in Ni-catalyzed Suzuki-Miyaura cross-coupling reactions. The C-sulfone bond in the alpha-oxo-vinylsulfone motif is cleaved chemoselectively in these reactions, furnishing C-aryl glycals or acyclic vinyl ethers in high yields. These reactions proceed under mild conditions and tolerate a remarkable scope of heterocycles and functional groups. Preliminary mechanistic studies revealed the importance of an alpha-heteroatom in facilitating these transformations.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 1034305-17-3. In my other articles, you can also check out more blogs about 1034305-17-3
Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem