Related Products of 1196-19-6, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1196-19-6, molcular formula is C9H7BrS, introducing its new discovery.
Treatment of 2-isocyano-N-<(S)-1'-phenylethyl>propionamide (3a) with butyllithium or potassium tert-butoxide (-70 deg C, tetrahydrofuran) initially causes metalation and subsequent (at ca. -20 deg C) cyclization to give the anionized 4-methyl-1-<(S)-1'-phenylethyl>-2-imidazolin-5-one (8).This reacts with benzyl or heterobenzyl halides to yield (4S)-4-benzyl- or (4S)-4-heterobenzyl-4-methyl-1-<(S)-1'-phenylethyl>-2-imidazolin-5-ones 9 with an asymmetric induction (d.e. = diastereomeric excess) >>95percent.Hydrolysis of 9 gives alpha-methylphenylalanine or its analogues of type 11 (nearly optically pure) which have been characterized as their N-acetyl derivatives 12.More over, (S)-1-phenylethylamine (2a), the chiral auxiliary compound, is recovered. – With non-benzylic alkyl halides d.e. is much lower (i.e. with allyl bromide 17percent, with cyclohexylmethyl iodide 35percent). – A model concept for the asymmetric induction which also explains the extremely high asymmetric induction with benzyl halides is proposed. – Methods for the synthesis of 2- unsubstituted 4-alkyl-2-imidazolin-5-ones (type 9a, 15-17) and 2-substituted 4-alkyl-2-imidazolin-5-ones (type 18-20) are described. – The X-ray analysis of 4-benzyl-4-methyl-1-(1′-phenylethyl)-2-imidazolin-5-one (9b) shows a) the “phenyl inside conformation” (folded conformation) for the C-4-benzyl group and b) C-1′ fixed in such a way that the hydrogen atom of the phenylethyl group lies in the heterocyclic plane, pointing towards the carbonyl oxygen.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1196-19-6 is helpful to your research. Related Products of 1196-19-6
Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem