Synthetic Route of 22913-24-2, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 22913-24-2, Name is Methyl benzo[b]thiophene-2-carboxylate, molecular formula is C10H8O2S. In a Article,once mentioned of 22913-24-2
Benzo[b]thiophene-2-carboxamide derivatives as potent urotensin-II receptor antagonists
Members of a series of benzo[b]thiophene-2-carboxamide derivatives, possessing an N-(1-(3-bromo-4-(piperidin-4-yloxy)benzyl)piperidin-4-yl) group, were synthesized and evaluated as urotensin-II receptor antagonists. The results show that these substances have potent UT binding affinities. Observations made in a systematic SAR investigation of the effects of a variety of substituents (R1and R2) at the 5- and 6-positions in the benzo[b]thiophene-2-carboxamide moiety on UT binding affinities led to identification of the 5-cyano analog 7f as a highly potent UT antagonist with an IC50value of 25 nM. Despite having a good metabolic stability, 7f is a potent inhibitor of CYP isozyme and displays an unsuitable PK profile.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 22913-24-2. In my other articles, you can also check out more blogs about 22913-24-2
Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem