Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. 33851-23-9, name is Methyl 7-chloro-3-hydroxybenzo[b]thiophene-2-carboxylate. In an article£¬Which mentioned a new discovery about 33851-23-9, Recommanded Product: Methyl 7-chloro-3-hydroxybenzo[b]thiophene-2-carboxylate.
Efficient synthesis and 5-LOX/COX-inhibitory activity of some 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives
A series of 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives has been prepared and subsequently evaluated with regards to the inhibition of 5-LOX/COX. Structure optimization furnished derivatives with promising in vitro activity as dual 5-LOX/COX inhibitors with submicromolar IC50 values for inhibition of 5-LOX and COX-1, respectively.
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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem