Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter. Safety of 2-Bromobenzo[b]thiophene, C8H5BrS. A document type is Article, introducing its new discovery., Safety of 2-Bromobenzo[b]thiophene
Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl, thiazolyl, and oxazolyl halides were efficiently difluoromethylated, thus providing medicinal chemists an alternative choice for the preparation of drug candidates with the difluoromethylated heteroarene unit.
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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem