Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. 4923-87-9, name is 5-Bromobenzothiophene. In an article£¬Which mentioned a new discovery about 4923-87-9, Product Details of 4923-87-9.
Palladium-Catalyzed alpha-Arylation of Carboxylic Acids and Secondary Amides via a Traceless Protecting Strategy
A novel traceless protecting strategy is presented for the long-standing challenge of conducting the palladium-catalyzed alpha-arylation of carboxylic aids and secondary amides with aryl halides. Both of the presented coupling processes occur with a variety of carboxylic acids and amides and with a variety of aryl bromides containing a broad range of functional groups, including base-sensitive functionality like acyl, alkoxycarbonyl, nitro, cyano, and even hydroxyl groups. Five commercial drugs were prepared through this method in one step in 81-96% yield. Gram-scale synthesis of medication Naproxen and Flurbiprofen with low palladium loading further highlights the practical value of this method.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Product Details of 4923-87-9, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 4923-87-9
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem