In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 14315-11-8, name is 4-Methylbenzo[b]thiophene, introducing its new discovery. Quality Control of 4-Methylbenzo[b]thiophene
Synthesis and Structure-Activity Relationship of Benzothienylallylamine Antimycotics
Benzothiophene analogues of the allylamine antimycotic terbinafine (2) bearing the side chain at various positions and optionally substituted by halogen have been prepared and their antifungal activity studied.Derivatives bearing the side chain at positions 3, 4, or 7 are bioequivalents of 2.Compounds containing the allylamine side chain at position 7, with a further substituent at position 3, showed significantly enhanced activity against Candida albicans, an effect which appears to be specifically linked only to this particular substitution pattern. 3-Chloro-7-benzothienyl derivative 7m was found to be the most potent allylamine antimycotic identified so far.In general, substituted benzothiophenes can be used not only as potential equivalents of naphthalene in bioactive compoudns but also as a tool to selectively modify biological activities.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 14315-11-8, and how the biochemistry of the body works.Quality Control of 4-Methylbenzo[b]thiophene
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem