In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C9H5ClO2S, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 26018-73-5, name is 6-Chlorobenzo[b]thiophene-2-carboxylic acid. In an article£¬Which mentioned a new discovery about 26018-73-5
SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
In the search of Factor Xa (FXa) inhibitors structurally different from the pyrazole-based series, we identified a viable series of enantiopure cis-(1R,2S)-cycloalkyldiamine derivatives as potent and selective inhibitors of FXa. Among them, cyclohexyldiamide 7 and cyclopentyldiamide 9 were the most potent neutral compounds, and had good anticoagulant activity comparable to the pyrazole-based analogs. Crystal structures of 7-FXa and 9-FXa illustrate binding similarities and differences between the five- and the six-membered core systems, and provide rationales for the observed SAR of P1 and linker moieties.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 26018-73-5, help many people in the next few years.Formula: C9H5ClO2S
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem