In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 90407-11-7, name is 7-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid, introducing its new discovery. Safety of 7-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid
Efficient synthesis and 5-LOX/COX-inhibitory activity of some 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives
A series of 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives has been prepared and subsequently evaluated with regards to the inhibition of 5-LOX/COX. Structure optimization furnished derivatives with promising in vitro activity as dual 5-LOX/COX inhibitors with submicromolar IC50 values for inhibition of 5-LOX and COX-1, respectively.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 90407-11-7, and how the biochemistry of the body works.Safety of 7-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem