In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 6287-82-7, name is 2,3-Dibromobenzo[b]thiophene, introducing its new discovery. HPLC of Formula: C8H4Br2S
Transition-Metal-Free Synthesis of Carbazoles and Indoles by an SNAr-Based “aromatic Metamorphosis” of Thiaarenes
Dibenzothiophene dioxides, which are readily prepared through oxidation of the parent dibenzothiophenes, undergo nucleophilic aromatic substitution with anilines intermolecularly and then intramolecularly to yield the corresponding carbazoles in a single operation. The “aromatic metamorphosis” of dibenzothiophenes into carbazoles does not require any heavy metals. This strategy is also applicable to the synthesis of indoles. Since electron-deficient thiaarene dioxides exhibit interesting reactivity, which is not observed for that the corresponding electron-rich azaarenes, a combination of a thiaarene-dioxide-specific reaction with the SNAr-based aromatic metamorphosis allows transition-metal-free construction of difficult-to-prepare carbazoles.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 6287-82-7, and how the biochemistry of the body works.HPLC of Formula: C8H4Br2S
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem