Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 5394-13-8, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 5394-13-8
Synthesis of 3-alkyl enol mimics inhibitors of type II dehydroquinase: Factors influencing their inhibition potency
Several 3-alkylaryl mimics of the enol intermediate in the reaction catalyzed by type II dehydroquinase were synthesized to investigate the effect on the inhibition potency of replacing the oxygen atom in the side chain by a carbon atom. The length and the rigidity of the spacer was also studied. The inhibitory properties of the reported compounds against type II dehydroquinase from Mycobacterium tuberculosis and Helicobacter pylori are also reported. The binding modes of these analogs in the active site of both enzymes were studied by molecular docking using GOLD 5.0 and dynamic simulations studies.
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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem