Reference of 5394-13-8, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 5394-13-8, Name is 2-Bromobenzo[b]thiophene,introducing its new discovery.
Ppm Pd-catalyzed, Cu-free Sonogashira couplings in water using commercially available catalyst precursors
A new catalyst that derives from commercially available precursors for copper-free, Pd-catalyzed Sonogashira reactions at the sustainable ppm level of precious metal palladium under mild aqueous micellar conditions has been developed. Both the palladium pre-catalyst and ligand are commercially available, bench stable, and highly cost-effective. The catalyst is applicable to both aryl- and heteroaryl-bromides as educts. A wide range of functional groups are tolerated and the aqueous reaction medium can be recycled. An application to a key intermediate associated with an active pharmaceutical ingredient (ponatinib) is discussed.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 5394-13-8, and how the biochemistry of the body works.Reference of 5394-13-8
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem