Extracurricular laboratory:new discovery of Benzo[b]thiophen-5-ol

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Chemistry is traditionally divided into organic and inorganic chemistry. name: Benzo[b]thiophen-5-ol, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 19301-35-0

Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors

A series of 3-heteroaryloxy-4-phenyl-2-(5H)-furanones were prepared and evaluated for their potency and selectivity as COX-2 inhibitors. This led to the identification of L-778,736 as a potent, orally active and selective inhibitor of the COX-2 enzyme.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem