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2,6-Bis(2-methylhydrazine-1-carbonyl)pyridine 1-oxide as an Efficient Ligand for Copper-Catalyzed C?N Coupling Reaction in Water

Abstract: Cu2O/2,6-bis(2-methylhydrazine-1-carbonyl)pyridine 1-oxide was found to be an efficiently catalytic system for the N-arylation of imidazole, indole, benzimidazole, pyrrole, benzylamine and ethanolamine with aryl iodides and bromides by using NaOH as base in the presence of 20?mol% (n-Bu)4NBr, and water as solvent at 130?C in 24?h, and giving the N-arylated products in moderate to excellent yields.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Final Thoughts on Chemistry for 6-Chlorobenzo[b]thiophene-2-carboxylic acid

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GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of alpha7- nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

The Absolute Best Science Experiment for 26018-73-5

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Reference of 26018-73-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.26018-73-5, Name is 6-Chlorobenzo[b]thiophene-2-carboxylic acid, molecular formula is C9H5ClO2S. In a Patent£¬once mentioned of 26018-73-5

Heteroaryl and benzyl amide compounds

Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Extracurricular laboratory:new discovery of Benzo[b]thiophen-5-ol

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Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors

A series of 3-heteroaryloxy-4-phenyl-2-(5H)-furanones were prepared and evaluated for their potency and selectivity as COX-2 inhibitors. This led to the identification of L-778,736 as a potent, orally active and selective inhibitor of the COX-2 enzyme.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Related Products of 4923-87-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 4923-87-9, 5-Bromobenzothiophene, introducing its new discovery.

MATERIAL FOR PHOTOELECTRIC CONVERSION ELEMENT FOR USE IN IMAGING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT INCLUDING SAME

?????????????(1)?????????????????????????????????????????????????????????????????????????????? The present invention provides a material for photoelectric conversion element for use in imaging element contain a compound represented by the following formula (1). The material can provide a photoelectric conversion element excellent in hole or electron leak prevention property, hole or electron transporting property, heat resistance against process temperature, visible light transparency and the like. (In the formula (1), R1and R2independently represent a substituted or unsubstituted heterocyclic condensed aromatic group).

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

A new application about 10243-15-9

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Sensitive Assays by Nucleophile-Induced Rearrangement of Photoactivated Diarylethenes

Upon light-induced isomerization, diarylethenes (DAEs) equipped with reactive aldehyde moieties rearrange selectively in the presence of amines, accompanied by decoloration. In a comprehensive study, the probe structure was optimized with regard to its inherent reactivity in the nucleophile-triggered rearrangement reaction. Detailed structure-reactivity relationships could be derived, in particular with regard to the type of integrated (het)aryl moieties as well as the location of the formyl residue, and the probes’ intrinsic reactivity with primary and secondary amines was optimized. Utilizing an ancillary base, the initially formed rearrangement product can engage in a subsequent catalytic cycle, leading to an amplified decoloration process. This additional catalytic pathway allows us to enhance the sensitivity of our method and successfully discriminate between amines and thiols. Moreover, probes that exhibit strong analyte-induced fluorescence modulation have been designed to further decrease the detection limit by using a more sensitive read-out. The optimized DAE probes are promising molecular components for future programmable sensing materials and devices.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Extended knowledge of 4-Methylbenzo[b]thiophene

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C9H8S, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 14315-11-8, name is 4-Methylbenzo[b]thiophene. In an article£¬Which mentioned a new discovery about 14315-11-8

HIGH-TEMPERATURE ORGANIC SYNTHESIS. XLII. REACTION OF HALOGENOARENES AND 2-CHLOROTHIOPHENE WITH HYDROGEN SULFIDE IN THE PRESENCE OF ACETYLENE

Benzothiophenes are formed with yields of more than 77percent in a single preparative stage during the gas-phase reaction of halogenoarenes with hydrogen sulfide and acetylene (600-700 deg C).It is suggested that arylthiyl radicals (ArS-radical), which are effectively captured by the acetylene, participate in the process.The effect of the structure of the halogenoarene on the selectivity of the process is discussed.The gas-phase reaction of 2-chlorothiophene with hydrogen sulfide in the presence of acetylene leads to the formation of thieno<2,3-b>thiophene.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Brief introduction of 6287-82-7

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Related Products of 6287-82-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.6287-82-7, Name is 2,3-Dibromobenzo[b]thiophene, molecular formula is C8H4Br2S. In a Patent£¬once mentioned of 6287-82-7

Condensed compound and organic light-emitting device comprising the same

Disclosed are a condensed cyclic compound and an organic light-emitting element comprising the same.COPYRIGHT KIPO 2016

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

A new application about 6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophene

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63675-74-1, Name is 6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophene, belongs to benzothiophene compound, is a common compound. Recommanded Product: 63675-74-1In an article, once mentioned the new application about 63675-74-1.

Benzothiophene compounds, intermediates, processes, compositions, and methods

The invention provides benzothiophene compounds, of formula I, STR1 wherein R1, R2, R3, R4 and n are as defined in the specification, formulations, and methods of inhibiting bone loss or bone resorption, particularly osteoporosis, and cardiovascular-related pathological conditions, including hyperlipidemia, and other cardiovascular pathologies.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Final Thoughts on Chemistry for Methyl 6-chlorobenzo[b]thiophene-2-carboxylate

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Palladium-catalyzed domino C-S coupling/carbonylation reactions: An efficient synthesis of 2-carbonylbenzo[ b ]thiophene derivatives

A facile and selective palladium-catalyzed domino procedure has been developed for the preparation of 2-carbonylbenzo[b]thiophene derivatives from 2-gem-dihalovinylthiophenols. This protocol involves intramolecular C-S coupling/intermolecular carbonylation cascade sequences and allows access to various highly functionalized benzo[b]thiophenes in moderate yields.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem