Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 22913-24-2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 22913-24-2, in my other articles.
One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 22913-24-2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 22913-24-2, Name is Methyl benzo[b]thiophene-2-carboxylate, molecular formula is C10H8O2S
Process for production of 2-substituted benzo[b]thiophene
The present invention provides a process for producing a 2-substituted benzo[b]thiophene, which is characterized by reacting a substituted or unsubstituted 2-halogenobenzaldehyde with sulfur and a compound represented by general formula (1) (wherein M represents an alkali metal; i represents an integer of 0 or 1; j represents an integer of 1 or more; and k represents an integer of 1-2 with a proviso that i+k=2), or with a compound of general formula (1) wherein j is 2 or more, in the presence of an aprotic polar solvent, and then reacting the reaction mixture with a compound represented by general formula (2) (wherein X represents a halogen atom; and R represents an acyl group, a substituted or unsubstituted alkoxycarbonyl group, a substituted or unsubstituted arylcarbonyl group or a cyano group) to give rise to intramolecular ring closure. The present process uses no unstable raw materials; enables production of an intended product in a simple operation at a high yield; and is very effective as a process for industrial production of 2-substituted benzo[b]thiophene.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 22913-24-2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 22913-24-2, in my other articles.
Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem