5381-20-4, Thianaphthene-3-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5381-20-4, To dry ethanol (20 mL) was added benzo[b]thiophene-3-carbaldehyde (246 mg, 1.52 mmol) and sodium borohydride (115 mg, 3.03 mmol), and the reaction was stirred at room temperature for 90 mins. When the reaction was complete by TLC, excess sodium borohydride was quenched with sodium hydroxide solution (1%, 20 mL), and the reaction was extracted with ethyl acetate (3 ¡Á 20 mL) before being dried (MgSO4), filtered and concentrated in vacuo to yield the title product in quantitative yield (249 mg). Rf = 0.40 (5:2 petroleum ether: ethyl acetate); 1H NMR (300 MHz, CDCl3): deltaH = 7.90 – 7.83 (2H, m, Ar), 7.44 – 7.34 (3H, m, Ar), 4.92 (2H, s, CH2), 1.95 (1H, br s, OH); 13C NMR (75 MHz, CDCl3) deltaC = 140.87 (Ar), 137.75 (Ar), 136.04 (Ar), 124.69 (Ar), 124.32 (Ar), 123.95 (Ar), 122.99 (Ar), 122.05 (Ar), 59.88 (CH2); MS (EI): m/z 164 (M).
5381-20-4 Thianaphthene-3-carboxaldehyde 227328, abenzothiophene compound, is more and more widely used in various fields.
Reference£º
Article; Sherer, Christopher; Tolaymat, Ibrahim; Rowther, Farzana; Warr, Tracy; Snape, Timothy J.; Bioorganic and Medicinal Chemistry Letters; vol. 27; 7; (2017); p. 1561 – 1565;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem