95-15-8,95-15-8, Thianaphthene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Under a nitrogen atmosphere, 10.0 g (0.075 mol) of benzo[b]thiophene and diethyl ether were loaded, and were then stirred at 0C. 51 Milliliters (0.082 mol) of 1.60-M n-butyllithium were dropped to the mixture and then the whole was stirred for 1 hour. After that, 2.6 g (0.082 mol) of sulfur were added to the resultant at 0C and then the mixture was stirred at room temperature for 6 hours. The reaction liquid was poured into ice water and then hydrochloric acid was used to adjust the pH of the mixture to 1, followed by the addition of 200 ml of diethyl ether. An organic layer was washed with distilled water (2¡Á100 ml). After that, the resultant organic layer was dried with anhydrous magnesium sulfate, and then magnesium sulfate was separated by filtration and the solvent was distilled off under reduced pressure. 100 Milliliters of tetrahydrofuran (THF) were added to the remainder, and then sodium borohydride was added to the mixture while the mixture was stirred at 0C, followed by stirring at room temperature for 2 hours. The reaction liquid was poured into ice water and then hydrochloric acid was used to adjust the pH of the mixture to 1, followed by the addition of 200 ml of diethyl ether. An organic layer was washed with distilled water (2¡Á100 ml). After that, the resultant organic layer was dried with anhydrous magnesium sulfate, and then magnesium sulfate was separated by filtration and the solvent was distilled off under reduced pressure. The resultant residue was purified by column chromatography to provide 11.2 g (0.067 mol, 89% yield) of an intermediate B-1.
95-15-8 Thianaphthene 7221, abenzothiophene compound, is more and more widely used in various fields.
Reference£º
Patent; Nippon Steel & Sumikin Chemical Co., Ltd.; SUDA Mitsuru; KAI Takahiro; MATSUMOTO Megumi; EP2628742; (2013); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem