17402-83-4, Benzo[b]thiophen-4-amine is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In a round bottom flask, 5.0 g 7-(4-(bis (2-chloroethyl) ammo) butoxy) quinolin-2(1H)-one, 20 ml n-butanol were taken at 25-35¡ã C. 2.29 g benzo[b]thiophen-4-amine was added into the reaction mixture at 25-35¡ã C. The reaction mixture was stirred at 110-125¡ã C. After completion of the reaction, the reaction mixture was cooled to 20-25 ¡ã C. and filtered and washed with toluene. The solid was dried in a hot air oven at 45-50¡ã C. to obtain brexpiprazole. The brexpiprazole can be purified by isopropanol and water. Yield: 90percent.
17402-83-4, As the paragraph descriping shows that 17402-83-4 is playing an increasingly important role.
Reference£º
Patent; CADILA HEALTHCARE LIMITED; DESAI, Sanjay Jagdish; PARIHAR, Jayprakash Ajitsingh; SHAH, Alpesh Pravinchandra; (21 pag.)US2017/320862; (2017); A1;,
Benzothiophene – Wikipedia
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