5381-20-4,5381-20-4, Thianaphthene-3-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: 3-(2-Methyl-5,6,7,8-hydrobenzo[4,5]-thieno[2,3-d]pyrimidin-4-yl)-2-thioxothiazolidin-4-one 7 (0.2 g,(0.60 mmol, 1 equiv) and aromatic aldehyde (0.77 mmol, 1.3 equiv). were thoroughly mixed then placedinto a specially designed microwave test tube containing 5 mL EtOH and three drops of piperidine. Thecharged tube was heated for 25 min at 100 C and 250 psi pressure. After cooling, the solid mass wasplaced in 50 mL cold EtOH and crushed. The slurry was filtered to give a solid that was washed severaltimes with EtOH/hexane mix (20%, v/v), then dried under vacuum to give the corresponding 5-aryl/hetaryl-2-thiocothiazolidine-4-one (8a-o) whose structures were identified by IR, LC/MS, GC/MS andNMR analysis. The physical and spectral properties of these compounds are shown later in the experimentalsection
The synthetic route of 5381-20-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Mendoza, Kimberly; Kamila, Sukanta; Biehl, Edward R.; Heterocycles; vol. 88; 1; (2014); p. 741 – 753;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem