3541-37-5, Benzo[b]thiophene-2-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: Aromatic o-bromoacetal 1 (1.0 mmol) was placed in the roundbottomflask (50 mL) and dissolved in dry THF (8 mL) at -78 C underargon atmosphere. Next, n-BuLi (1.1 mmol, 2.5M in hexanes) wasadded. The resulting mixture was stirred for 15 min. under argon andthen aromatic aldehyde 2 (1.2 mmol) was added in dry THF. Stirringwas continued for 2 h at -78 C and the reaction mixture was warmedto room temperature. Saturated aqueous NH4Cl solution was added andthe solvent was evaporated. The residue was diluted with ethyl acetate(3×10 mL), washed with water (15 mL) and dried over anhydrousMgSO4. After filtration, ethyl acetate was removed in vacuum and thecrude product 3 was purified by column chromatography over silica gelwith a mixture of petroleum ether/acetone (4:1 v/v)., 3541-37-5
3541-37-5 Benzo[b]thiophene-2-carboxaldehyde 736500, abenzothiophene compound, is more and more widely used in various fields.
Reference£º
Article; Ba?czewski, Piotr; Kowalska, Emilia; Skalik, Joanna; Koprowski, Marek; Owsianik, Krzysztof; Ro?ycka-Soko?owska, Ewa; Ultrasonics Sonochemistry; vol. 58; (2019);,
Benzothiophene – Wikipedia
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