130-03-0, Benzo[b]thiophen-3(2H)-one is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of AN-1 (6 g, 3.99 mmol) in EtOH (60 mL) is added N2H4 hydrate (31.1 ml). The mixture is heated to reflux for 45 min. The mixture is cooled to rt and then concentrated. The residue is dissolved in diethylene glycol (20 mL) and KOH (6.72 g, 120 mmol) is added. The mixture is stirred at 120 C for 18 h. The mixture is cooled to rt, diluted with EtOAc and the pH is adjusted with IN HC1 to pH < 4. The organic layers are washed with brine, dried over Na2S04 and concentrated. The residue is purified by Si02 flash chromatography to yield AN-2., 130-03-0
The synthetic route of 130-03-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BAKONYI, Johanna; BRUNETTE, Steven Richard; COLLIN, Delphine; HUGHES, Robert Owen; LI, Xiang; LIANG, Shuang; SIBLEY, Robert; TURNER, Michael Robert; WU, Lifen; ZHANG, Qiang; WO2015/160654; (2015); A1;,
Benzothiophene – Wikipedia
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