With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.95-15-8,Thianaphthene,as a common compound, the synthetic route is as follows.
95-15-8, Benzothiophene is n- butyl lithium and reaction of the intermediate obtained after the homo coupling reaction proceeds M63-1 (homocoupling reaction) under the action of anhydrous yeomhwadong After obtaining the lithium salt through a NBS bromination homo bromide M63-2 after getting the n- butyl lithium and reaction to obtain a pair bromide M63-4 through the NBS bromination and then generate a lithium salt, and the intermediate obtained through the homo-coupled anti-M63-3 under the action of anhydrous methyl N- yeomhwadong to give a compound of boric acid and 3-M63 via a Suzuki coupling reaction (white solid, yield 53%).
The synthetic route of 95-15-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Kunshan visionox Display Company Limited; Beijing Dingchai Technology Company Limited; Beijing visionox Technology Company Limited; Tsinghua University; Chiu, Yong; Pan, Hong Tao; Wang, Sing; Duan, Leanne; Run, Syueien; (77 pag.)KR2015/65184; (2015); A;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem