Analyzing the synthesis route of 5381-20-4

5381-20-4 Thianaphthene-3-carboxaldehyde 227328, abenzothiophene compound, is more and more widely used in various fields.

5381-20-4,5381-20-4, Thianaphthene-3-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Dehydroacetic acid (500 mg, 2.97 mmol),3-formaldehyde benzothiophene (482.34 mg, 2.97 mmol) was dissolved in CHCl3 (4 ml).Piperidine (2d) was added dropwise,Nitrogen protection, reaction at 60 C for 12 h.The post-processing operation is the same as in Embodiment 1,A yellow solid was obtained, 507 mg (yield 54.59%).

5381-20-4 Thianaphthene-3-carboxaldehyde 227328, abenzothiophene compound, is more and more widely used in various fields.

Reference£º
Patent; Jiangsu Hengrui Pharmaceutical Co., Ltd.; You Qidong; Hu Wenyuan; Jiang Zhengyu; Guo Xiaoke; Xu Xiaoli; Zhang Xiaojin; (14 pag.)CN107629041; (2018); A;,
Benzothiophene – Wikipedia
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