20532-33-6, 5-Chlorobenzothiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
[000541j To a solution of Compound 41A (500 mg, 2.97 mmol) in THF (30 mL) was added n-BuLi (1.42 ml, 3.56 mmol) at -78 C under the protection of nitrogen. Then it was stirred at -78 C for 1 h, DMF (434 mg, 5.94 mmol) was added to the mixture and stirred for another one hour at -78 C. The reaction was quenched with sat. NH4C1. After separation, the organic phase was washed with brine, and dried over anhydrous Na2SO4, and purified by silica gel column chromatography (ethyl acetate in petroleum 20% v/v) to render Compound 41B. ?H-NMR (CDC13, 400 MHz) major characteristic peaks: (5(ppm) 7.47 (dd, J= 2.0, 8.8 Hz, 1H), 7.83 (d,J= 8.8 Hz, 1H), 7.93(d,J= 2.0 Hz, 1H), 7.97 (s, 1H), 10.11 (s, 1H)., 20532-33-6
As the paragraph descriping shows that 20532-33-6 is playing an increasingly important role.
Reference£º
Patent; BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; WO2015/65937; (2015); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem