With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.20699-85-8,Methyl 5-aminobenzo[b]thiophene-2-carboxylate,as a common compound, the synthetic route is as follows.
A mixture of 500 mg of methyl 5-aminobenzo[b]thiophene-2-carboxylate, 320 mg of acetic anhydride, 623 mgof diisopropylethylamine, and 10 ml of dichloromethane was stirred for 4 hours at room temperature. The reaction mixturewas washed with an aqueous saturated sodium hydrogen carbonate solution and saturated saline, dried over magnesiumsulfate, and concentrated under reduced pressure. The residues were subjected to silica gel column chromatography,thereby obtaining 449 mg of methyl 5-(acetylamino)benzo[b]thiophene-2-carboxylate., 20699-85-8
As the paragraph descriping shows that 20699-85-8 is playing an increasingly important role.
Reference£º
Patent; Sumitomo Chemical Company Limited; MUKUMOTO, Fujio; TAMAKI, Hiroaki; KUSAKA, Shintaro; IWAKOSHI, Mitsuhiko; EP2926660; (2015); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem