4923-87-9, 5-Bromobenzothiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The air in the flask was replaced with nitrogen. 5-bromobenzo [b] thiophene (10.44 g, 49.0 mmol) and Ni (dppp) Cl 2 (1.27 g, 2.33 mmol) were placed in the flask and 200 mL of diethyl ether was added.Thereafter, a 2.0 M solution of octyl magnesium bromide in diethyl ether (35.25 mL, 70.5 mmol) was slowly added dropwise, and the mixture was stirred at room temperature for 12 hours.Water was added to the obtained solution, and the mixture was extracted with hexane. The organic phase was dried by adding sodium sulfate.The hydrate of sodium sulfate was filtered, the filtrate was collected, and the solvent was distilled off from the filtrate using an evaporator.The obtained material was purified by column chromatography (silica gel, developing solvent: hexane) to obtain Compound 1 as a black liquid (yield = 10.0 g, 82.9%)., 4923-87-9
4923-87-9 5-Bromobenzothiophene 2776578, abenzothiophene compound, is more and more widely used in various fields.
Reference£º
Patent; KYUSHU UNIVERSITY; KYOCERA CORPORATION; YASUDA, TAKUMA; MORI, TATSUYA; OHYAMA, TATSUYA; TAKEDA, KEIZO; (44 pag.)JP2017/210449; (2017); A;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem