With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1127-35-1,Benzo[b]thiophene-3(2H)-one 1,1-Dioxide,as a common compound, the synthetic route is as follows.
Under nitrogen atmosphere, 100mL round bottom flask was charged sulfone group indanone (728mg, 4.0mmol), malononitrile (1.32g, 20.0mol) and absolute ethanol (11mL).Was then added anhydrous sodium acetate (656mg, 8.0mol), stirred at rt overnight, the reaction was completed hydrochloric acid to adjust the pH 1-2, then filtered, washed with deionized water 3-5 times, and dried in vacuo to give a white solid (847mg, yield 92%)., 1127-35-1
The synthetic route of 1127-35-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Chinese Academy Of Sciences Ningbo Materials Technology And Engineering Institute; Fang Junfeng; Zhang Wenjun; Song Changjian; (26 pag.)CN109232604; (2019); A;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem