346592-74-3, 7-Fluorobenzo[b]thiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 4-1Preparation of Compound 4-7 [0507j Compound 4-6 (12 g, 79 mmol) and dichloromethyl methyl ether (13.5, 118 mmol) were dissolved in anhydrous DCM (400 mL). To the solution was added titanium tetrachloride (23 g, 122 mmol). After stirring at rt for 1 h, the mixture was poured into a mixture of saturated aqueous NaHCO3 and ice. The mixture was stirred for about 30 mins and then extracted with DCM. The organic layer was dried over sodium sulfate and concentrated. The residue was purified by column chromatograph on silica gel (PE:EA=80: 1 to 20:1) to give 4-7 (6.0 g, 40 %). ?H-NMR (400MHz, d-DMSO), &10.14 (d, J1.0 Hz, 1 H), 9.05 (s, 1 H), 8.36-8.34 (m, 1 H), 7.60-7.55 (m, 1 H), 7.4 1-7.37 (m, 1 H)., 346592-74-3
The synthetic route of 346592-74-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ALIOS BIOPHARMA, INC.; WANG, Guangyi; BEIGELMAN, Leonid; TRUONG, Anh; NAPOLITANO, Carmela; ANDREOTTI, Daniele; HE, Haiying; WO2014/31784; (2014); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem