Downstream synthetic route of 17347-32-9

17347-32-9, The synthetic route of 17347-32-9 has been constantly updated, and we look forward to future research findings.

17347-32-9, 6-Bromobenzothiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 6-bromobenzothiophene (500 mg, 2.35 mmol) in DMF (6 ml) was added Zn(CN)2 (413 mg, 3.52 mmol) and Pd(PPh3)4 (136 mg, 0.117 mmol). The reaction was heated in the microwave to 100 C for 30 min. The mixture was filtered through a pad of Celite with EtOAc, the solvents were removed in vacuo and the crude product was purified by flash chromatography using 10-20%) EtOAc in n- heptane as eluent. Yield: 325 mg (87%); yellow solid. HPLC purity: 100 %.

17347-32-9, The synthetic route of 17347-32-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; KANCERA AB; HAMMER, Kristin; JOeNSSON, Mattias; KRUeGER, Lars; (230 pag.)WO2017/108282; (2017); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem