3541-37-5, Benzo[b]thiophene-2-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Thiosemicarbazide (1.82 g, 20.0 mmol) was added to a stirredsolution of benzo [b]thiophene-2-carboxaldehyde (1) (3.24 g,20.0 mmol) in absolute ethyl alcohol (40 ml) and then (1.0 ml) ofacetic acid was added. The reaction mixture was stirred underreflux for 20 h, cooled to room temperature and separate precipitatewas collected by filtration, washed with ethyl alcohol to affordthe desired product to yield 3.90 g (83%); mp 218-219 C, mp219-220 C [22]; eluent: dichloromethane/methanol (95:5),Rf 0.67.1H NMR (DMSO-d6) d(ppm): 7.35-7.43 (m, 2H, 2CHAr);7.59 (bs, 1H, NH2); 7.77 (s, 1H, CH); 7.81-7.86 (m, 1H, CHAr);7.91-7.96 (m, 1H, CH); 8.32 (bs, 1H, NH2); 8.37 (s, 1H, CH]N); 11.62(bs, 1H, NH). 13C NMR (DMSO-d6) d(ppm): 122.98 (C); 124.74 (C);125.28 (C); 126.44 (C); 128.16 (C); 138.27 (C); 139.63 (C); 139.78 (C);139.85 (C); 178.34 (C]S)., 3541-37-5
The synthetic route of 3541-37-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Rosada, Beata; Bekier, Adrian; Cytarska, Joanna; P?azi?ski, Wojciech; Zavyalova, Olga; Sikora, Adam; Dzitko, Katarzyna; ??czkowski, Krzysztof Z.; European Journal of Medicinal Chemistry; vol. 184; (2019);,
Benzothiophene – Wikipedia
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