5381-25-9, 1-Benzothiophene-3-carboxylic acid is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5381-25-9
To a stirred solution OF 4- [ (Z)- (4-BROMOPHENYL) (ethoxyimino) methyl]-1- (4-methyl-4- piperidinyl) piperidine (50 mg, 0.12 MMOL), benzo [b] thiophene-3-carboxylic acid (22 mg, 0.13 MMOL), and Et3N (24.3 mg, 0.24 MMOL) in DMF (2 ML), HATU (61 mg, 0.16 MMOL) was added at room temperature. After 16 h the mixture was poured into ice water (10 mL), and was extracted with CH2CI2 (3X10 mL). The organic phase was dried over NA2SO4, and concentrated in vacuo. Purification by preparative TLC afforded title compound as a white solid. MS: 569 (M++1).
The synthetic route of 5381-25-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SCHERING AKTIENGESELLSCHAFT; WO2004/113323; (2004); A1;,
Benzothiophene – Wikipedia
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