5381-20-4, Thianaphthene-3-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5381-20-4
4-Phenyl-piperidine-1-sulfonic acid amide (1.5 g, 6.24 mmol) was dissolved in ethanol (20 mL). Benzo[b]thiophene-3-carbaldehyde (1.0 g, 6.24 mmol) was then added and the reaction mixture was warmed to 45 C. overnight. The reaction mixture was cooled to room temperature and then treated with sodium borohydride (0.2 g, 5.29 mmol). The reaction was then quenched by addition of 1 N HCl. The reaction mixture was stirred overnight. The product precipitated from solution and was removed by vacuum filtration to yield the title compound as a white solid. 1H NMR (DMSO-d6): delta 7.99 (2H, q, J=12.0, 7.7 Hz), 7.86 (1H, dd, J=5.0 Hz), 7.66 (1H, s), 7.42 (2H, dt, J=14.0, 6.7 Hz), 7.35-7.24 (3H, m), 7.24-7.09 (2H, m), 4.37 (2H, d, J=5.8 Hz), 3.56 (2H, d, J=11.5 Hz), 2.75-2.59 (3H, m), 1.68 (2H, d, J=13.5 Hz), 1.31 (2H, dd, J=25.0, 13.5 Hz).
As the paragraph descriping shows that 5381-20-4 is playing an increasingly important role.
Reference£º
Patent; Abdel-Magid, Ahmed F.; Mehrman, Steven J.; US2006/270856; (2006); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem