With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.3541-37-5,Benzo[b]thiophene-2-carboxaldehyde,as a common compound, the synthetic route is as follows.
[0054] Calixarene 6 (benzothiophene-resorcinol calix[4]arene,) was prepared by the following method. To a 250 mL round bottom flask, resorcinol (2.00 g, 18.2 mmol), benzo[b]thiophene-2-carboxaldehyde (2.95 g, 18.2 mmol), ethanol (100 mL), and HCl (concentrated, 10 mL) were added. A nitrogen inlet was equipped and the reaction was stirred at 80 C. for 16 h. The reaction began as a clear solution but slowly formed a purple precipitate. After completion of the reaction, the resulting solution was filtered through a fritted funnel and the solid collected was washed with water (50 mL) and ethanol (50 mL). The washed product was dried in vacuo at 60 C. for 16 hours (yield: 4.05 g, 88%). LC-MS m/z=1017.2 g/mol.
3541-37-5, 3541-37-5 Benzo[b]thiophene-2-carboxaldehyde 736500, abenzothiophene compound, is more and more widely used in various fields.
Reference£º
Patent; ROHM AND HAAS ELECTRONIC MATERIALS LLC; Green, D. Patrick; Jain, Vipul; Bailey, Brad C.; US2013/157195; (2013); A1;,
Benzothiophene – Wikipedia
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