3541-37-5, Benzo[b]thiophene-2-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a stirred solution of Mg turnings (15mmol) and iodine (two pieces) in dry diethyl ether (10mL) at room temperature equipped with a reflux condenser was added dropwise a mixture of allylbromide (11mmol) in anhydrous diethyl ether (5mL). The mixture was allowed to reflux for 30min. Then, the mixture was cooled down to 0C followed by dropwise addition of the corresponding aldehyde (benzofuran or benzothiophene) (10mmol) in dry diethylether (3mL). The resultant mixture was then stirred for 3h. The reaction mixture was hydrolyzed with saturated ammonium chloride solution (10mL) and then with 1M HCl (2mL). The resultant mixture was then extracted with diethyl ether (3¡Á30mL). The combined organic phase was washed with brine (20mL) and dried over MgSO4 and evaporated in vacuo. The crude products were purified by flash column chromatography with ethyl acetate/hexane mixture (1:5)., 3541-37-5
The synthetic route of 3541-37-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Bueyuekadal?, Nalan Nuriye; Aslan, Nezir; Guemue?, Selcuk; Guemue?, Ay?eguel; Tetrahedron Asymmetry; vol. 27; 19; (2016); p. 954 – 959;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem