With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.3541-37-5,Benzo[b]thiophene-2-carboxaldehyde,as a common compound, the synthetic route is as follows.
the 0.162g (1 mmol) of benzothiophene-2-carbaldehyde and 0.119g (1mmol) of ethyl thiosemicarbazide placed in a 20ml of round bottom flask, then added 2-3ml of Absolute ethanol as a solvent, followed by the dropwise addition of 2-4 drops of glacial acetic acid, stirred at reflux for 10 mins at 80 C under shade. The reaction was Cool at room temperature, a white solid precipitated, suction filtered, recrystallized from ethanol to give a white product 1- (Benzothiophen-2- methylene) -4-ethyl- thiosemicarbazide, yield 84%, Melting point: 200.3-201.2 C. The white powder turned bright yellow after being irradiated with UV light at 365 nm. The bright yellow solid turned pale yellowish after visible light irradiation., 3541-37-5
As the paragraph descriping shows that 3541-37-5 is playing an increasingly important role.
Reference£º
Patent; Xinjiang University; Liu Lang; Qiao Yuqian; Jia Dianzeng; (8 pag.)CN107298674; (2017); A;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem