1423-61-6, 7-Bromobenzo[b]thiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 6; Preparation of Compound 49; Step A – Synthesis of Compound 49 A; A solution of 7-bromothiophene (8.0 g, 37.5 mmol) in ether (50 mL) was cooled to -78 C and treated dropwise with n-BuLi (1.6 M solution in hexanes, 1.0 eq.) and the resulting reaction was allowed to stir at -78 C for 20 minutes. The reaction mixture was then diluted with DMF (dry 5.4 g, 67.4 mmol) and allowed to stirat -78 0C for 1 hour. The reaction mixture was then diluted with water and extracted into ether. The combined organic layers were dried (MgSO4), filtered, concentrated in vacuo and purified using flash column chromatography on silica gel to provide compound 49A as a colorless liquid.; Example 7; Preparation of Compound 52; Step A – Synthesis of Compound 52A; A solution of 7-bromothiophene (8.0 g, 37.5 mmol) in ether (50 mL) was cooled to -78 C, then n-BuLi (1.6 M soln in hexanes, 1.0 eq.) was added dropwise and the resulting reaction was allowed to stir at -78 0C for 20 minutes. The reaction mixture was diluted with DMF (dry 5.4 g, 67.4 mmol) and allowed to stir at -78 0C for 1 hour. The reaction mixture was then quenched with water and the resulting solution was extracted into ether. The combined organic layers were dried (MgSO4), filtered, and concentrated in vacuo to provide a crude residue which was purified using flash column chromatography on silica gel to provide compound 52A as a colorless liquid., 1423-61-6
1423-61-6 7-Bromobenzo[b]thiophene 12045538, abenzothiophene compound, is more and more widely used in various.
Reference£º
Patent; SCHERING CORPORATION; WO2008/82484; (2008); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem