5381-20-4, Thianaphthene-3-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5381-20-4, General procedure: To a resealable Schlenk tube was added MCM-41-PPh3-AuNTf2 (192mg, 0.05mmol). The reaction tube was evacuated and back-filled with argon and this evacuation/back-fill procedure was repeated one additional time. Aldehyde (1.0mmol), propargylamine (4.0mmol), water (5.0mmol), and DCE (4mL) were then added under a stream of argon. The reaction tube was quickly sealed and the mixture was stirred at 40C until disappearance of the starting material (TLC, typically 48h). After being cooled to room temperature, the reaction mixture was diluted with ethyl acetate (20mL) and filtered. The catalyst was washed with ethyl acetate (2¡Á5mL) and diethyl ether (2¡Á5mL), and reused in the next run. The filtrate was concentrated under reduced pressure and the residue was purified by flash chromatography (petroleum ether/ethyl acetate mixtures) to afford the corresponding product.
The synthetic route of 5381-20-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Short Survey; Nie, Quan; Yao, Fang; Yi, Feiyan; Cai, Mingzhong; Journal of Organometallic Chemistry; vol. 846; (2017); p. 343 – 350;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem