1423-61-6, 7-Bromobenzo[b]thiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Combine 7-bromo-benzo[b] thiophene (426 mg, 2 mmol), bis-(pinacolato)- diboron (756 mg, 3 mmol), Pd(dppf)Cl2 (81 mg, 0.1 mmol), potassium acetate (294 mg, 3 mmol) in dimethyl sulfoxide (DMSO) (10 mL) in a flask. Bubble nitrogen through the mixture for 5 minutes (min). Seal the flask and place it into an oil bath to heat at 100 0C for 4 hours (h). Dilute the mixture with chloroform/isopropyl alcohol (IPA) (3/1). Wash the solution with aqueous saturated sodium chloride. Dry over sodium sulfate. Concentrate the solution in vacuo to a dark residue. Purify by column chromatography (hexane-^ 20 % ethyl acetate in hexane) to give the title compound as a colorless solid (342 mg, 66 %). MS (ES) m/z 261 [M+l]+., 1423-61-6
The synthetic route of 1423-61-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ELI LILLY AND COMPANY; WO2008/144223; (2008); A2;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem